RVS

This is the development version of RVS; for the stable release version, see RVS.

Computes estimates of the probability of related individuals sharing a rare variant

Bioconductor version: Development (3.21)

Rare Variant Sharing (RVS) implements tests of association and linkage between rare genetic variant genotypes and a dichotomous phenotype, e.g. a disease status, in family samples. The tests are based on probabilities of rare variant sharing by relatives under the null hypothesis of absence of linkage and association between the rare variants and the phenotype and apply to single variants or multiple variants in a region (e.g. gene-based test).

Author: Alexandre Bureau, Ingo Ruczinski, Samuel Younkin, Thomas Sherman

Maintainer: Alexandre Bureau <alexandre.bureau at fmed.ulaval.ca>

Citation (from within R, enter citation("RVS")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("RVS")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("RVS")

The RVS Package	HTML	R Script
Reference Manual	PDF
NEWS	Text

Need some help? Ask on the Bioconductor Support site!

Details

biocViews	ExomeSeq, Genetics, GenomeWideAssociation, ImmunoOncology, Software, VariantDetection, WholeGenome
Version	1.29.0
In Bioconductor since	BioC 3.6 (R-3.4) (7 years)
License	GPL-2
Depends	R (>= 3.5.0)
Imports	GENLIB, gRain, snpStats, kinship2, methods, stats, utils, R.utils
System Requirements
URL

Suggests	knitr, testthat, rmarkdown, BiocStyle, VariantAnnotation
Linking To
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report	Build Report

Package Archives

Follow Installation instructions to use this package in your R session.

Source Package	RVS_1.29.0.tar.gz
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository	git clone https://git.bioconductor.org/packages/RVS
Source Repository (Developer Access)	git clone git@git.bioconductor.org:packages/RVS
Bioc Package Browser	https://code.bioconductor.org/browse/RVS/
Package Short Url	https://bioconductor.org/packages/RVS/
Package Downloads Report	Download Stats