RnaSeqSampleSize

This package is for version 3.21 of Bioconductor. This package has been removed from Bioconductor. For the last stable, up-to-date release version, see RnaSeqSampleSize.

RnaSeqSampleSize


Bioconductor version: Development (3.21)

RnaSeqSampleSize package provides a sample size calculation method based on negative binomial model and the exact test for assessing differential expression analysis of RNA-seq data. It controls FDR for multiple testing and utilizes the average read count and dispersion distributions from real data to estimate a more reliable sample size. It is also equipped with several unique features, including estimation for interested genes or pathway, power curve visualization, and parameter optimization.

Author: Shilin Zhao Developer [aut, cre], Chung-I Li [aut], Yan Guo [aut], Quanhu Sheng [aut], Yu Shyr [aut]

Maintainer: Shilin Zhao Developer <zhaoshilin at gmail.com>

Citation (from within R, enter citation("RnaSeqSampleSize")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("RnaSeqSampleSize")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

Reference Manual PDF

Details

biocViews DifferentialExpression, ExperimentalDesign, GeneExpression, ImmunoOncology, RNASeq, Sequencing, Software
Version 2.17.0
In Bioconductor since BioC 3.1 (R-3.2) (9.5 years)
License GPL (>= 2)
Depends R (>= 4.0.0), ggplot2, RnaSeqSampleSizeData
Imports biomaRt, edgeR, heatmap3, matlab, KEGGREST, methods, grDevices, graphics, stats, Rcpp (>= 0.11.2), recount, ggpubr, SummarizedExperiment, tidyr, dplyr, tidyselect, utils
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Follow Installation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repository git clone https://git.bioconductor.org/packages/RnaSeqSampleSize
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/RnaSeqSampleSize
Package Short Url https://bioconductor.org/packages/RnaSeqSampleSize/
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