tspair

This package is for version 3.0 of Bioconductor; for the stable, up-to-date release version, see tspair.

Top Scoring Pairs for Microarray Classification

Bioconductor version: 3.0

These functions calculate the pair of genes that show the maximum difference in ranking between two user specified groups. This "top scoring pair" maximizes the average of sensitivity and specificity over all rank based classifiers using a pair of genes in the data set. The advantage of classifying samples based on only the relative rank of a pair of genes is (a) the classifiers are much simpler and often more interpretable than more complicated classification schemes and (b) if arrays can be classified using only a pair of genes, PCR based tests could be used for classification of samples. See the references for the tspcalc() function for references regarding TSP classifiers.

Author: Jeffrey T. Leek <jtleek at jhu.edu>

Maintainer: Jeffrey T. Leek <jtleek at jhu.edu>

Installation

To install this package, start R and enter:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("tspair")

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("tspair")

Details

Package Archives

Follow Installation instructions to use this package in your R session.