ELViS

This is the development version of ELViS; to use it, please install the devel version of Bioconductor.

An R Package for Estimating Copy Number Levels of Viral Genome Segments Using Base-Resolution Read Depth Profile


Bioconductor version: Development (3.21)

Base-resolution copy number analysis of viral genome. Utilizes base-resolution read depth data over viral genome to find copy number segments with two-dimensional segmentation approach. Provides publish-ready figures, including histograms of read depths, coverage line plots over viral genome annotated with copy number change events and viral genes, and heatmaps showing multiple types of data with integrative clustering of samples.

Author: Hyo Young Choi [aut, cph] (ORCID: ), Jin-Young Lee [aut, cre, cph] (ORCID: ), Xiaobei Zhao [ctb] (ORCID: ), Jeremiah R. Holt [ctb] (ORCID: ), Katherine A. Hoadley [aut] (ORCID: ), D. Neil Hayes [aut, fnd, cph] (ORCID: )

Maintainer: Jin-Young Lee <jlee307 at uthsc.edu>

Citation (from within R, enter citation("ELViS")):

Installation

To install this package, start R (version "4.5") and enter:


if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("ELViS")

For older versions of R, please refer to the appropriate Bioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("ELViS")
Authoring R Markdown vignettes HTML R Script
Reference Manual PDF
NEWS Text
LICENSE Text

Details

biocViews BiomedicalInformatics, Clustering, CopyNumberVariation, Coverage, GenomicVariation, Normalization, Sequencing, Software, Visualization
Version 0.99.10
In Bioconductor since BioC 3.21 (R-4.5)
License MIT + file LICENSE
Depends R (>= 4.5.0)
Imports basilisk, BiocGenerics, circlize, ComplexHeatmap, data.table, dplyr, GenomicFeatures, GenomicRanges, ggplot2, glue, graphics, grDevices, igraph, IRanges, magrittr, memoise, methods, parallel, patchwork, scales, segclust2d, stats, stringr, txdbmaker, utils, uuid, zoo
System Requirements
URL https://github.com/hyochoi/ELViS
Bug Reports https://github.com/hyochoi/ELViS/issues
See More
Suggests Rsamtools, BiocManager, knitr, testthat (>= 3.0.0)
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Package Archives

Follow Installation instructions to use this package in your R session.

Source Package ELViS_0.99.10.tar.gz
Windows Binary (x86_64)
macOS Binary (x86_64) ELViS_0.99.10.tgz
macOS Binary (arm64) ELViS_0.99.10.tgz
Source Repository git clone https://git.bioconductor.org/packages/ELViS
Source Repository (Developer Access) git clone git@git.bioconductor.org:packages/ELViS
Bioc Package Browser https://code.bioconductor.org/browse/ELViS/
Package Short Url https://bioconductor.org/packages/ELViS/
Package Downloads Report Download Stats